Mutagenicity refers to the induction of permanent transmissible changes in the amount or structure of
the genetic material in cells or organisms. These changes may involve a single gene (point mutations),
a block of genes or entire chromosomes (structural or numerical chromosome aberrations).

Source: JRC Technical Report Review of QSAR Models and Software Tools for Predicting Genotoxicity and Carcinogenicity EUR 24427, EN - 2010.