The "Lowest concentration of interest" (LCI) approach is the most feasible strategy for assessing the health effects of compounds from building materials.
The LCI concept was originally developed by a group of leading European scientists as part of a basic scheme for the evaluation of VOC emissions from building products and was published in 1997 in ECA report No. 18.
It was recommended that “Lowest concentrations of interest” (LCI) should be derived on the basis of either air quality guideline values (AQG) or occupational exposure limits as auxiliary parameters for the assessment of the health risks resulting from exposure to chemicals emitted from building materials.
The concept of LCI values was adopted and further developed/revised in the German AgBB scheme and in the French AFSSET (now ANSES) protocol for the health related evaluation of VOC emissions from building products.

Source: JRC, Outcome of the EU Workshop on “Harmonisation of the health based evaluation of
emissions from building products in the EU using the LCI-concept” -13-14 September 2010, Ispra (Italy)


  • Lowest concentration of interest