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Cyclotron technical overview

 

CyclotronOverview of the facility

  • Model: Scandotronix MC40
  • Commissioned in 1982
  • Proton, deuteron, 4He2⁺ and 3He2⁺ beams available
  • Variable particle energy
  • 3 Irradiation halls
  • 7 external beamlines

 

Equipment and Laboratories

  • Gamma and Alpha Spectrometers
  • Glove Boxes for radiochemistry separations
  • Hot laboratories in the controlled area
  • Hot Workshop
  • Dedicated intrumentation for material studies (e.g. DLS for nanoparticle size
    analysis and zeta potential, X-ray diffractometer)
  • Solid and Liquid phase target systems
  • Neutron ‘Adiabatic Resonance Crossing’ (ARC) target for radioisotope production

 

Cyclotron beam characteristics

Particle

Maximum Energy
(MeV)

Maximum Extracted
Current (µA)

protons

 

40

 

60

4He2⁺ (α)

 

40

 

30

3He2

53

 

30

deuterons

 

20

 

60

 

Nanoparticles activation techniques

  • Direct NP irradiation
  • Recoil implantation
  • Neutron irradiation via ARC system

 
Radioisotope production and research use

  • 18F-FDG production under GMP (Good Manufacturing Practice) in collaboration with General Electric Healthcare
  • 7Be for nanoparticle recoil implantation labelling method (AlO, MWCNT, SiO)

  • 48V for titanium dioxide nanoparticle labelling
  • 56Co for silica nanoparticle radiolabelling
  • 105Ag for radiolabelling of silver nanoparticles
  • 198Au and 166Ho for cancer brachytherapy studie
  • Alpha-emitters for alpha immunotherapy application
  • 64Cu for both beta therapy and PET
  • 186Re for beta therapy
  • 86Y, 44Sc and 43Sc radionuclides for PET

 

Competitive projects, collaborations and networks

  • General Electric Healthcare commercial collaboration
  • Partner of QNANO project: the EU-funded infrastructure for nanomaterial safety testing (http://www.qnano-ri.eu/)
  • Member of the European Cyclotron Network (CYCLEUR)
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