JRC scientists contribute to 'Concern-driven integrated approaches to nanomaterial testing and assessment'
New publication aims at identifying key areas for further research on risk assessment methodologies for nanomaterials
|Contact Name||JRC-IHCP, Nanotechnology|
This paper, published in May 2013, presents a vision for concern-driven integrated approaches for the (eco-)toxicological testing and assessment (IATA) of nanomaterials (NM).
By effectively exploiting all available information and focusing on the so-called non-testing methods (methods which don't employ animal testing) such as the analysis of structure-activity relationships (SAR), IATA allows accelerating the risk assessment process, reducing animal use and testing costs.
Combining material properties, exposure, biokinetics, and hazard data, information gained with IATA can be used to recognize groups of NM based upon similar modes-of-action. The resulting grouping of substances should then be integrated into the IATA approach.
The paper is authored by the Working Group 10 of the “NanoSafety Cluster” - an initiative that brings together topic-related EU-funded projects, aiming at identifying key areas for further research on risk assessment procedures for nanomaterials.
"Concern-driven integrated approaches to nanomaterial testing and assessment - Report of the NanoSafety Cluster Working Group 10", by A. Oomen, P. Bos, T. F. Fernandes, K. Hund-Rinke, D. Borschi, H. J. Byrne, K. Aschberger, S. Gottardo, F. von der Kammer, D. Kühnel, D. Hristozov, A. Marcomini, L. Migliore, J. J. Scott-Fordsmand, P. Wick, R. Landsiedel. Posted online on May 6, 2013. doi:10.3109/17435390.2013.802387