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Hazard Assessment of Multiwall Carbon Nanotubes using Balb/3T3 cells to assess the carcinogenic potential

— filed under: risk assessment, cancer, in-vitro methods, nanotech, nanotoxicology, safety, nanomaterials, nanobiosciences

In collaboration with scientists from the Italian Institute for Health (Istituto Superiore di Sanità) JRC scientists investigated the carcinogenic potential of pure and chemically functionalised multiwall carbon nanotubes using the Balb/3T3 cells. Results showed no cytotoxicity nor genotoxicity , but some morphological transformation through cell intraction of nanomaterials could be observed pointing towards a carcinogenic potential. The scientists recommend the integration of various tests, also based on physicochemical characterization of the nanomaterials to clearly evaluate the potential toxicity of nanomaterials.

NanoBiotech Laboratory, Joint Research Centre, Institute for Health and Consumer Protection. Copyright EU 2011.

Contact Name	JRC-IHCP, Nanotechnology

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Watch it on You Tube, JRC channel

Related terms: genotoxicity

hazard

nanotechnology

cytotoxicity

hazard assessment

BALB/3T3 cells

nanomaterials

health

carbon nanotubes

As the Commission's in-house science service, the Joint Research Centre's mission is to provide EU policies with independent, evidence-based scientific and technical support throughout the whole policy cycle. Working in close cooperation with policy Directorates-General, the JRC addresses key societal challenges while stimulating innovation through developing new methods, tools and standards, and sharing its know-how with the Member States, the scientific community and international partners. Key policy areas include: environment and climate change; energy and transport; agriculture and food security; health and consumer protection; information society and digital agenda; safety and security, including nuclear; all supported through a cross-cutting and multidisciplinary approach.

Last update: Mar 22, 2012

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